It seems I have also just hit this bug. I am able to trigger hangs on my
Sapphire Nitro+ Radeon RX 580 Special Edition on the first fight with ghouls
after Geralt awakes from his dream at the beginning of the game using wine
3.13. It does not happen all the time, but when I do the fight a few times,
there is eventually a point where it freezes.

I am using mesa git on commit c3eaf8fe5746e5b29a46a076247ba072c84e2ec5 and
kernel 4.17.9 with the Gentoo patchset.