I guess you mean that the GPIO callbacks include Runtime PM handling however for irq_chip Runtime PM may not be hooked up so the GPIO block is in such case is not powered on / get clock enabled?
Yes. There is another drawback when GPIOs are not properly requested. It is still possible to request them from userspace although a kernel driver is using them. I am playing with the idea that the GPIO core auto-requests GPIOs which are not already requested but still set up as interrupts.