I am having similar issue on AMD HD 7870 GPU, openSUSE Tumbleweed, and Kernel 4.4.0-1.2. I cannot say for sure the trigger, however, once the screen locks requiring a password, the password field becomes disabled although mouse and keyboard remain fully functional. In fact, it would seem the entire lock screen becomes unresponsive to both mouse and keyboard, and CTRL+ALT+Backspace needs to be employed in order to restart the session.