Connected to this bug report on WineHQ: https://bugs.winehq.org/show_bug.cgi?id=47389 Confirmed for Mesa 18.3.6. R100-class GPU too (ATI Mobility Radeon 7000 IGP). R100 class Radeon GPUs only support OpenGL up to 1.3, while GLSL has only become a thing as an extension for 1.4 and finally an integral feature in 2.0. Does that mean OpenGL Shading Language support is nowadays necessary for Mesa?