Double post, but it wasn't so clear in this thread up to now: The game will
only really use compute shaders when OpenGL is 4.3, not when it is 4.2.

With the mesa override to version 4.3 I can find calls like
604839 @3 glDispatchCompute(num_groups_x = 256, num_groups_y = 1, num_groups_z
= 1)
in the apitrace, without the override I do not see those.

So here is an apitrace with 4.3fc override:
http://haagch.frickel.club/files/AlienIsolation.trace.xz
(1.3 Gigabyte download)