I was going to create a new bug but I think my issue may be the same. With llvm-svn up to revision 267861 everything works fine, but starting with revision 268162 I get the same issue as in Ersnt's screenshot. My console prints many of these : LLVM triggered Diagnostic Handler: LDS size exceeds device maximum LLVM failed to compile shader radeonsi: can't create a shader Card is 280x so a bit different. I am on latest mesa-git, and linux 4.5 (patched to get computer shader). Downgrading llvm-svn fixes the issue right away.