https://bugzilla.kernel.org/show_bug.cgi?id=202445
--- Comment #14 from Nicholas Kazlauskas (nicholas.kazlauskas@amd.com) --- FreeSync not working on WINE is a Mesa issue I believe.
I don't think the backend WINE goes through is DRI3 which is required to use the present extension / support page-flipping through X to DRM.
The flickering I'm not quite sure about. I don't think I've observed it happening lately in amd-staging-drm-next on Raven or Vega when running any of the Unigine benchmarks at varying settings (dipping below and into the VRR range).
Do you mind booting with drm.debug=4 and posting a dmesg log when you're running the Unigine Valley benchmark? It would also help to know what desktop environment/compositor you're using.