https://bugs.freedesktop.org/show_bug.cgi?id=82455
--- Comment #5 from Michel Dänzer michel@daenzer.net --- (In reply to comment #3)
In theory it should work, but that doesn't mean there might be a lot of bugs.
Actually, it most definitely can't work right now. Just for one thing, every memory access by shaders (for constants, resource descriptors, ...) currently can't work correctly on big endian hosts.